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Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors

Phosphatidylethanolamine (PE) made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the enzyme that makes PE in the mitochondrion, phosphatidylserine...

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Detalles Bibliográficos
Autores principales: Sam, Pingdewinde N., Calzada, Elizabeth, Acoba, Michelle Grace, Zhao, Tian, Watanabe, Yasunori, Nejatfard, Anahita, Trinidad, Jonathan C., Shutt, Timothy E., Neal, Sonya E., Claypool, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921845/
https://www.ncbi.nlm.nih.gov/pubmed/33718843
http://dx.doi.org/10.1016/j.isci.2021.102196