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Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors
Phosphatidylethanolamine (PE) made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the enzyme that makes PE in the mitochondrion, phosphatidylserine...
Autores principales: | Sam, Pingdewinde N., Calzada, Elizabeth, Acoba, Michelle Grace, Zhao, Tian, Watanabe, Yasunori, Nejatfard, Anahita, Trinidad, Jonathan C., Shutt, Timothy E., Neal, Sonya E., Claypool, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921845/ https://www.ncbi.nlm.nih.gov/pubmed/33718843 http://dx.doi.org/10.1016/j.isci.2021.102196 |
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