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Targeting FBXO44/SUV39H1 elicits tumor cell-specific DNA replication stress and viral mimicry
Repetitive elements (REs) are normally transcriptionally silenced in somatic cells by repressive epigenetic modifications, which are thought to include DNA methylation and histone modifications such as deacetylation, H3K9me3, and H4K20me3. Although, it is unclear how RE silencing is maintained throu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shared Science Publishers OG
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921849/ https://www.ncbi.nlm.nih.gov/pubmed/33681705 http://dx.doi.org/10.15698/cst2021.03.245 |