Spermidine supplementation in rare translation-associated disorders

The polyamine spermidine is essential for protein translation in eukaryotes, both as a substrate for the hypusination of the translation initiation factor eIF5A as well as general translational fidelity. Dwindling spermidine levels during aging have been implicated in reduced immune cell function th...

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Detalles Bibliográficos
Autores principales: Zimmermann, Andreas, Carmona-Gutierrez, Didac, Madeo, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921850/
https://www.ncbi.nlm.nih.gov/pubmed/33688620
http://dx.doi.org/10.15698/cst2021.03.243