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Antineuroinflammatory Effects of 7,3’,4’-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression

Neuroinflammation—a common pathological feature of neurodegenerative disorders such as Alzheimer’s disease—is mediated by microglial activation. Thus, inhibiting microglial activation is vital for treating various neurological disorders. 7,3’,4’-Trihydroxyisoflavone (THIF)—a secondary metabolite of...

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Detalles Bibliográficos
Autores principales: Kim, Seon-Kyung, Ko, Yong-Hyun, Lee, Youyoung, Lee, Seok-Yong, Jang, Choon-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921860/
https://www.ncbi.nlm.nih.gov/pubmed/32812529
http://dx.doi.org/10.4062/biomolther.2020.093