Novel Complex of PD-L1 Aptamer and Holliday Junction Enhances Antitumor Efficacy in Vivo

Blocking the PD-1/PD-L1 pathway can diminish immunosuppression and enhance anticancer immunity. PD-1/PD-L1 blockade can be realized by aptamers, which have good biocompatibility and can be synthesized in quantity economically. For in vivo applications, aptamers need to evade renal clearance and nucl...

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Detalles Bibliográficos
Autores principales: Li, Ting, Yao, Fengjiao, An, Yacong, Li, Xundou, Duan, Jinhong, Yang, Xian-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921949/
https://www.ncbi.nlm.nih.gov/pubmed/33670583
http://dx.doi.org/10.3390/molecules26041067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921949/
https://www.ncbi.nlm.nih.gov/pubmed/33670583
http://dx.doi.org/10.3390/molecules26041067

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