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Developing a Vaccine to Block West Nile Virus Transmission: In Silico Studies, Molecular Characterization, Expression, and Blocking Activity of Culex pipiens mosGCTL-1

Background: Mosquito galactose-specific C-type lectins (mosGCTLs), such as mosGCTL-1, act as ligands to facilitate the invasion of flaviviruses like West Nile virus (WNV). WNV interacts with the mosGCTL-1 of Aedes aegypti (Culicidae) and facilitates the invasion of this virus. Nevertheless, there is...

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Detalles Bibliográficos
Autores principales: Bakhshi, Hasan, Fazlalipour, Mehdi, Dadgar-Pakdel, Javad, Zakeri, Sedigheh, Raz, Abbasali, Failloux, Anna-Bella, Dinparast Djadid, Navid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921969/
https://www.ncbi.nlm.nih.gov/pubmed/33671430
http://dx.doi.org/10.3390/pathogens10020218