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Lysines Acetylome and Methylome Profiling of H3 and H4 Histones in Trichostatin A—Treated Stem Cells

Trichostatin A ([R-(E,E)]-7-[4-(dimethylamino) phenyl]-N-hydroxy- 4,6-dimethyl- 7-oxo-2,4-heptadienamide, TSA) affects chromatin state through its potent histone deacetylase inhibitory activity. Interfering with the removal of acetyl groups from lysine residues in histones is one of many epigenetic...

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Detalles Bibliográficos
Autores principales: Cozzolino, Flora, Iacobucci, Ilaria, Monaco, Vittoria, Angrisano, Tiziana, Monti, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921975/
https://www.ncbi.nlm.nih.gov/pubmed/33669725
http://dx.doi.org/10.3390/ijms22042063