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Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies

Eosinophils are implicated in the pathophysiology of a spectrum of eosinophil-associated diseases, including gastrointestinal eosinophilic diseases (EGIDs). Biologics that target the IL-5 pathway and are intended to ablate eosinophils have proved beneficial in severe eosinophilic asthma and may offe...

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Detalles Bibliográficos
Autores principales: Masterson, Joanne C., Menard-Katcher, Calies, Larsen, Leigha D., Furuta, Glenn T., Spencer, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922004/
https://www.ncbi.nlm.nih.gov/pubmed/33671475
http://dx.doi.org/10.3390/cells10020426