Extracellular Vesicle-Derived microRNAs of Human Wharton’s Jelly Mesenchymal Stromal Cells May Activate Endogenous VEGF-A to Promote Angiogenesis

Despite low levels of vascular endothelial growth factor (VEGF)-A, the secretome of human Wharton’s jelly (WJ) mesenchymal stromal cells (MSCs) effectively promoted proangiogenic responses in vitro, which were impaired upon the depletion of small (~140 nm) extracellular vesicles (EVs). The isolated...

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Detalles Bibliográficos
Autores principales: Chinnici, Cinzia Maria, Iannolo, Gioacchin, Cittadini, Ettore, Carreca, Anna Paola, Nascari, David, Timoneri, Francesca, Bella, Mariangela Di, Cuscino, Nicola, Amico, Giandomenico, Carcione, Claudia, Conaldi, Pier Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922033/
https://www.ncbi.nlm.nih.gov/pubmed/33669517
http://dx.doi.org/10.3390/ijms22042045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922033/
https://www.ncbi.nlm.nih.gov/pubmed/33669517
http://dx.doi.org/10.3390/ijms22042045

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