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Extracellular Vesicle-Derived microRNAs of Human Wharton’s Jelly Mesenchymal Stromal Cells May Activate Endogenous VEGF-A to Promote Angiogenesis
Despite low levels of vascular endothelial growth factor (VEGF)-A, the secretome of human Wharton’s jelly (WJ) mesenchymal stromal cells (MSCs) effectively promoted proangiogenic responses in vitro, which were impaired upon the depletion of small (~140 nm) extracellular vesicles (EVs). The isolated...
Autores principales: | Chinnici, Cinzia Maria, Iannolo, Gioacchin, Cittadini, Ettore, Carreca, Anna Paola, Nascari, David, Timoneri, Francesca, Bella, Mariangela Di, Cuscino, Nicola, Amico, Giandomenico, Carcione, Claudia, Conaldi, Pier Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922033/ https://www.ncbi.nlm.nih.gov/pubmed/33669517 http://dx.doi.org/10.3390/ijms22042045 |
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