Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis

Bone metastases frequently occur in breast cancer patients and lack appropriate treatment options. Hence, understanding the molecular mechanisms involved in the multistep process of breast cancer bone metastasis and tumor-induced osteolysis is of paramount interest. The serine/threonine kinase AKT p...

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Detalles Bibliográficos
Autores principales: Hinz, Nico, Baranowsky, Anke, Horn, Michael, Kriegs, Malte, Sibbertsen, Freya, Smit, Daniel J., Clezardin, Philippe, Lange, Tobias, Schinke, Thorsten, Jücker, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922044/
https://www.ncbi.nlm.nih.gov/pubmed/33670586
http://dx.doi.org/10.3390/cells10020430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922044/
https://www.ncbi.nlm.nih.gov/pubmed/33670586
http://dx.doi.org/10.3390/cells10020430

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