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Heightened Crescentic Glomerulonephritis in Immune Challenged 129sv Mice Is TGF-β/Smad3 Dependent

The 129sv mouse strain is particularly sensitive to experimental immune-mediated nephritis. Previous studies have indicated that transforming growth factor-β (TGF-β) plays a critical role in both immune modulation and tissue fibrogenesis in various diseases and that its biological activities are exe...

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Detalles Bibliográficos
Autores principales: Du, Yong, Xie, Chun, Ravikumar, Sneha, Orme, Jacob, Li, Li, Zhou, Xin J, Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922100/
https://www.ncbi.nlm.nih.gov/pubmed/33669690
http://dx.doi.org/10.3390/ijms22042059