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Mapping of Genomic Vulnerabilities in the Post-Translational Ubiquitination, SUMOylation and Neddylation Machinery in Breast Cancer

SIMPLE SUMMARY: Breast cancer is a major cause of death worldwide and remains incurable in advanced stages. The dysregulation of the post-translational machinery has been found to underlie tumorigenesis and drug resistance in preclinical models but has only recently led to early trials in cancer pat...

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Detalles Bibliográficos
Autores principales: Fuentes-Antrás, Jesús, Alcaraz-Sanabria, Ana Lucía, Morafraile, Esther Cabañas, Noblejas-López, María del Mar, Galán-Moya, Eva María, Baliu-Pique, Mariona, López-Cade, Igor, García-Barberán, Vanesa, Pérez-Segura, Pedro, Manzano, Aránzazu, Pandiella, Atanasio, Győrffy, Balázs, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922122/
https://www.ncbi.nlm.nih.gov/pubmed/33671201
http://dx.doi.org/10.3390/cancers13040833