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The Role of SNP Interactions when Determining Independence of Novel Signals in Genetic Association Studies—An Application to ARG1 and Bronchodilator Response

Genome-wide association studies (GWAS) play a critical role in identifying many loci for common diseases and traits. There has been a rapid increase in the number of GWAS over the past decade. As additional GWAS are being conducted, it is unclear whether a novel signal associated with the trait of i...

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Detalles Bibliográficos
Autores principales: Walsh, Ryan, Voorhies, Kirsten, McDonald, Merry-Lynn, McGeachie, Michael, Sordillo, Joanne E., Lange, Christoph, Wu, Ann Chen, Lutz, Sharon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922125/
https://www.ncbi.nlm.nih.gov/pubmed/33669563
http://dx.doi.org/10.3390/jpm11020145