p62-Induced Cancer-Associated Fibroblast Activation via the Nrf2-ATF6 Pathway Promotes Lung Tumorigenesis

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAF) arise from normal fibroblasts within the tumor microenvironment (TME) and promote tumorigenesis through metabolic reprograming and secretion of tumor promoting molecules such as transforming growth factor beta (TGFβ). Here, we show that autophagy p...

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Detalles Bibliográficos
Autores principales: Kang, Ji In, Kim, Dong Hyun, Sung, Ki Woon, Shim, Sang Mi, Cha-Molstad, Hyunjoo, Soung, Nak Kyun, Lee, Kyung Ho, Hwang, Joonsung, Lee, Hee Gu, Kwon, Yong Tae, Kim, Bo Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922306/
https://www.ncbi.nlm.nih.gov/pubmed/33670717
http://dx.doi.org/10.3390/cancers13040864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922306/
https://www.ncbi.nlm.nih.gov/pubmed/33670717
http://dx.doi.org/10.3390/cancers13040864

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