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Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway

Idiopathic pulmonary fibrosis (IPF) is a fatal and age-related pulmonary disease. Nintedanib is a receptor tyrosine kinase inhibitor, and one of the only two listed drugs against IPF. Regorafenib is a novel, orally active, multi-kinase inhibitor that has similar targets to nintedanib and is applied...

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Detalles Bibliográficos
Autores principales: Li, Xiaohe, Ma, Ling, Huang, Kai, Wei, Yuli, Long, Shida, Liu, Qinyi, Zhang, Deqiang, Wu, Shuyang, Wang, Wenrui, Yang, Guang, Zhou, Honggang, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922359/
https://www.ncbi.nlm.nih.gov/pubmed/33671452
http://dx.doi.org/10.3390/ijms22041985