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Antibody-Oligonucleotide Conjugates: A Twist to Antibody-Drug Conjugates

A summary of the key technological advancements in the preparation of antibody–oligonucleotide conjugates (AOCs) and the distinct advantages and disadvantages of AOCs as novel therapeutics are presented. The merits and demerits of the different approaches to conjugating oligonucleotides to antibodie...

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Detalles Bibliográficos
Autores principales: Dugal-Tessier, Julien, Thirumalairajan, Srinath, Jain, Nareshkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922418/
https://www.ncbi.nlm.nih.gov/pubmed/33670689
http://dx.doi.org/10.3390/jcm10040838