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Loss of parla Function Results in Inactivity, Olfactory Impairment, and Dopamine Neuron Loss in Zebrafish

The presenilin-associated rhomboid-like (PARL) gene was found to contribute to mitochondrial morphology and function and was linked to familial Parkinson’s disease (PD). The PARL gene product is a mitochondrial intramembrane cleaving protease that acts on a number of mitochondrial proteins involved...

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Detalles Bibliográficos
Autores principales: Merhi, Rawan, Kalyn, Michael, Zhu-Pawlowsky, Amanda, Ekker, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922472/
https://www.ncbi.nlm.nih.gov/pubmed/33670667
http://dx.doi.org/10.3390/biomedicines9020205