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Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges

Autism spectrum disorder (ASD) represents a group of neurodevelopmental diseases characterized by persistent deficits in social communication, interaction, and repetitive patterns of behaviors, interests, and activities. The etiopathogenesis is multifactorial with complex interactions between geneti...

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Detalles Bibliográficos
Autores principales: Villa, Chiara, Combi, Romina, Conconi, Donatella, Lavitrano, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922555/
https://www.ncbi.nlm.nih.gov/pubmed/33669772
http://dx.doi.org/10.3390/pharmaceutics13020280