Human Ccr4 and Caf1 Deadenylases Regulate Proliferation and Tumorigenicity of Human Gastric Cancer Cells via Modulating Cell Cycle Progression

SIMPLE SUMMARY: Cancer cells generally reprogram their gene expression profiles to satisfy continuous growth, proliferation, and metastasis. Most eukaryotic mRNAs are degraded in a deadenylation-dependent pathway, in which deadenylases are the key enzymes. We found that human Ccr4 (hCcr4a/b) and Caf...

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Detalles Bibliográficos
Autores principales: Song, Xiao-Hui, Liao, Xiao-Yan, Zheng, Xu-Ying, Liu, Jia-Qian, Zhang, Zhe-Wei, Zhang, Li-Na, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922635/
https://www.ncbi.nlm.nih.gov/pubmed/33671234
http://dx.doi.org/10.3390/cancers13040834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922635/
https://www.ncbi.nlm.nih.gov/pubmed/33671234
http://dx.doi.org/10.3390/cancers13040834

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