Study of Endogen Substrates, Drug Substrates and Inhibitors Binding Conformations on MRP4 and Its Variants by Molecular Docking and Molecular Dynamics

Multidrug resistance protein-4 (MRP4) belongs to the ABC transporter superfamily and promotes the transport of xenobiotics including drugs. A non-synonymous single nucleotide polymorphisms (nsSNPs) in the ABCC4 gene can promote changes in the structure and function of MRP4. In this work, the interac...

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Detalles Bibliográficos
Autores principales: Becerra, Edgardo, Aguilera-Durán, Giovanny, Berumen, Laura, Romo-Mancillas, Antonio, García-Alcocer, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922701/
https://www.ncbi.nlm.nih.gov/pubmed/33671368
http://dx.doi.org/10.3390/molecules26041051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922701/
https://www.ncbi.nlm.nih.gov/pubmed/33671368
http://dx.doi.org/10.3390/molecules26041051

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