Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva

Fibrodysplasia ossificans progressiva (FOP) is an ultrarare congenital disease that progresses through intermittent episodes of bone formation at ectopic sites. FOP patients carry heterozygous gene point mutations in activin A receptor type I ACVR1, encoding the bone morphogenetic protein (BMP) type...

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Detalles Bibliográficos
Autores principales: Ventura, Francesc, Williams, Eleanor, Ikeya, Makoto, Bullock, Alex N., ten Dijke, Peter, Goumans, Marie-José, Sanchez-Duffhues, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922784/
https://www.ncbi.nlm.nih.gov/pubmed/33669809
http://dx.doi.org/10.3390/biomedicines9020213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922784/
https://www.ncbi.nlm.nih.gov/pubmed/33669809
http://dx.doi.org/10.3390/biomedicines9020213

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