Decitabine Inhibits Bone Resorption in Periodontitis by Upregulating Anti-Inflammatory Cytokines and Suppressing Osteoclastogenesis

DNA methylation controls several inflammatory genes affecting bone homeostasis. Hitherto, inhibition of DNA methylation in vivo in the context of periodontitis and osteoclastogenesis has not been attempted. Ligature-induced periodontitis in C57BL/6J mice was induced by placing ligature for five days...

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Detalles Bibliográficos
Autores principales: Tanaka, Urara, Kajioka, Shunichi, Finoti, Livia S., Palioto, Daniela B., Kinane, Denis F., Benakanakere, Manjunatha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922804/
https://www.ncbi.nlm.nih.gov/pubmed/33671221
http://dx.doi.org/10.3390/biomedicines9020199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922804/
https://www.ncbi.nlm.nih.gov/pubmed/33671221
http://dx.doi.org/10.3390/biomedicines9020199

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