Non-Genetically Encoded Epitopes Are Relevant Targets in Autoimmune Diabetes

Islet antigen reactive T cells play a key role in promoting beta cell destruction in type 1 diabetes (T1D). Self-reactive T cells are typically deleted through negative selection in the thymus or deviated to a regulatory phenotype. Nevertheless, those processes are imperfect such that even healthy i...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai, Guyer, Perrin, Ettinger, Ruth A., James, Eddie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922826/
https://www.ncbi.nlm.nih.gov/pubmed/33671312
http://dx.doi.org/10.3390/biomedicines9020202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922826/
https://www.ncbi.nlm.nih.gov/pubmed/33671312
http://dx.doi.org/10.3390/biomedicines9020202

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