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Non-Genetically Encoded Epitopes Are Relevant Targets in Autoimmune Diabetes
Islet antigen reactive T cells play a key role in promoting beta cell destruction in type 1 diabetes (T1D). Self-reactive T cells are typically deleted through negative selection in the thymus or deviated to a regulatory phenotype. Nevertheless, those processes are imperfect such that even healthy i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922826/ https://www.ncbi.nlm.nih.gov/pubmed/33671312 http://dx.doi.org/10.3390/biomedicines9020202 |