Cargando…

DNA Methyltransferase 1 (DNMT1) Shapes Neuronal Activity of Human iPSC-Derived Glutamatergic Cortical Neurons

Epigenetic mechanisms are emerging key players for the regulation of brain function, synaptic activity, and the formation of neuronal engrams in health and disease. As one important epigenetic mechanism of transcriptional control, DNA methylation was reported to distinctively modulate synaptic activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Bachmann, Sarah, Linde, Jenice, Bell, Michael, Spehr, Marc, Zempel, Hans, Zimmer-Bensch, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922860/
https://www.ncbi.nlm.nih.gov/pubmed/33670788
http://dx.doi.org/10.3390/ijms22042034