Cargando…
DNA Methyltransferase 1 (DNMT1) Shapes Neuronal Activity of Human iPSC-Derived Glutamatergic Cortical Neurons
Epigenetic mechanisms are emerging key players for the regulation of brain function, synaptic activity, and the formation of neuronal engrams in health and disease. As one important epigenetic mechanism of transcriptional control, DNA methylation was reported to distinctively modulate synaptic activ...
Autores principales: | Bachmann, Sarah, Linde, Jenice, Bell, Michael, Spehr, Marc, Zempel, Hans, Zimmer-Bensch, Geraldine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922860/ https://www.ncbi.nlm.nih.gov/pubmed/33670788 http://dx.doi.org/10.3390/ijms22042034 |
Ejemplares similares
-
DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons
por: Hahn, Anne, et al.
Publicado: (2020) -
DNA Methyltransferase 1 (DNMT1) Acts on Neurodegeneration by Modulating Proteostasis-Relevant Intracellular Processes
por: Bayer, Cathrin, et al.
Publicado: (2020) -
DNMT1-dependent regulation of cortical interneuron function and survival
por: Pensold, Daniel, et al.
Publicado: (2021) -
Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks
por: Symmank, Judit, et al.
Publicado: (2020) -
DNA Methylation-Dependent Dysregulation of GABAergic Interneuron Functionality in Neuropsychiatric Diseases
por: Linde, Jenice, et al.
Publicado: (2020)