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p38 MAPK Inhibition Mitigates Hypoxia-Induced AR Signaling in Castration-Resistant Prostate Cancer

SIMPLE SUMMARY: Progression of prostate cancer to a castration-resistant state is associated with poor patient outcomes, and new therapeutic targeting approaches are needed. Poorly oxygenated (hypoxic) cancer cells are resistant to many treatment modalities, and it is therefore important that novel...

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Detalles Bibliográficos
Autores principales: Cheung, Serina, Jain, Pallavi, So, Jonathan, Shahidi, Saeid, Chung, Stephen, Koritzinsky, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922949/
https://www.ncbi.nlm.nih.gov/pubmed/33671134
http://dx.doi.org/10.3390/cancers13040831