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Zoom in on Antibody Aggregates: A Potential Pitfall in the Search of Rare EV Populations

High-resolution flow cytometers (hFCM) are used for the detection of extracellular vesicles (EV) in various biological fluids. Due to the increased sensitivity of hFCM, new artifacts with the potential of interfering with data interpretation are introduced, such as detection of antibody aggregates....

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Detalles Bibliográficos
Autores principales: Rasmussen, Rikke W., Botha, Jaco, Prip, Frederik, Sanden, Mathilde, Nielsen, Morten H., Handberg, Aase
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923005/
https://www.ncbi.nlm.nih.gov/pubmed/33670624
http://dx.doi.org/10.3390/biomedicines9020206