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Changes in Apoptotic Pathways in MOLM-13 Cell Lines after Induction of Resistance to Hypomethylating Agents

We established the following two variants of the MOLM-13 human acute myeloid leukemia (AML) cell line: (i) MOLM-13/DAC cells are resistant to 5-aza-2′-deoxycytidine (DAC), and (ii) MOLM-13/AZA are resistant to 5-azacytidine (AZA). Both cell variants were obtained through a six-month selection/adapta...

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Detalles Bibliográficos
Autores principales: Janotka, Ľuboš, Messingerová, Lucia, Šimoničová, Kristína, Kavcová, Helena, Elefantová, Katarína, Sulová, Zdena, Breier, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923013/
https://www.ncbi.nlm.nih.gov/pubmed/33669837
http://dx.doi.org/10.3390/ijms22042076