Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage

Gout is a type of inflammatory arthritis caused by the deposition of monosodium uric acid (MSU) crystals in tissues. The etiology of gout is directly linked to the NLRP3 inflammasome, since MSU crystals are NLRP3 inflammasome activators. Therefore, we decided to search for a small-molecule inhibitor...

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Detalles Bibliográficos
Autores principales: Choi, Nuri, Yang, Gabsik, Jang, Joo Hyeon, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923023/
https://www.ncbi.nlm.nih.gov/pubmed/33670601
http://dx.doi.org/10.3390/molecules26041071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923023/
https://www.ncbi.nlm.nih.gov/pubmed/33670601
http://dx.doi.org/10.3390/molecules26041071

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