Ratiometric Fluorescence Assay for Nitroreductase Activity: Locked-Flavylium Fluorophore as a NTR-Sensitive Molecular Probe

Nitroreductases belong to a member of flavin-containing enzymes that can reduce nitroaromatic compounds to amino derivatives with NADH as an electron donor. NTR activity is known to be elevated in the cancerous environment and is considered an advantageous target in therapeutic prodrugs for the trea...

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Detalles Bibliográficos
Autores principales: Kim, Su Jung, Yoon, Jung Won, Yoon, Shin A, Lee, Min Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923055/
https://www.ncbi.nlm.nih.gov/pubmed/33669590
http://dx.doi.org/10.3390/molecules26041088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923055/
https://www.ncbi.nlm.nih.gov/pubmed/33669590
http://dx.doi.org/10.3390/molecules26041088

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