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Suppression of the HBP Function Increases Pancreatic Cancer Cell Sensitivity to a Pan-RAS Inhibitor

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death and the search for a resolutive therapy is still a challenge. Since KRAS is commonly mutated in PDAC and is one of the main drivers of PDAC progression, its inhibition should be a key strategy for treatment, especiall...

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Detalles Bibliográficos
Autores principales: Ricciardiello, Francesca, Bergamaschi, Laura, De Vitto, Humberto, Gang, Yang, Zhang, Taiping, Palorini, Roberta, Chiaradonna, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923121/
https://www.ncbi.nlm.nih.gov/pubmed/33670598
http://dx.doi.org/10.3390/cells10020431