Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Spleen tyrosine kinase (SYK) can behave as an oncogene or a tumor suppressor, depending on the cell and tissue type. As pharmacological SYK inhibitors are currently evaluated in clinical trials, it is important to gain more information on the molecular mechanisms underpinning these opposite roles. T...

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Detalles Bibliográficos
Autores principales: Buffard, Marion, Naldi, Aurélien, Freiss, Gilles, Deckert, Marcel, Radulescu, Ovidiu, Coopman, Peter J., Larive, Romain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923165/
https://www.ncbi.nlm.nih.gov/pubmed/33670716
http://dx.doi.org/10.3390/biom11020308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923165/
https://www.ncbi.nlm.nih.gov/pubmed/33670716
http://dx.doi.org/10.3390/biom11020308

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