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Detection of Somatic Mutations with ddPCR from Liquid Biopsy of Colorectal Cancer Patients

Liquid biopsy and cell-free DNA (cfDNA) show great promise in cancer diagnostics. In this study, we designed a custom droplet digital PCR (ddPCR) assay for the quantification and quality control of cfDNA isolated from serum. The assay was validated on a group of locally advanced colorectal cancer (C...

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Detalles Bibliográficos
Autores principales: Zmrzljak, Uršula Prosenc, Košir, Rok, Krivokapić, Zoran, Radojković, Dragica, Nikolić, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923234/
https://www.ncbi.nlm.nih.gov/pubmed/33669856
http://dx.doi.org/10.3390/genes12020289