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Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer

BACKGROUND: WD repeat domain 3 (WDR3) is involved in a variety of cellular processes including gene regulation, cell cycle progression, signal transduction and apoptosis. However, the biological role of WDR3 in pancreatic cancer and the associated mechanism remains unclear. We seek to explore the im...

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Detalles Bibliográficos
Autores principales: Su, Wenjie, Zhu, Shikai, Chen, Kai, Yang, Hongji, Tian, Mingwu, Fu, Qiang, Shi, Ganggang, Feng, Shijian, Ren, Dianyun, Jin, Xin, Yang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923337/
https://www.ncbi.nlm.nih.gov/pubmed/33648545
http://dx.doi.org/10.1186/s13046-021-01879-w