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Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study

BACKGROUND: The low carbohydrate, high fat ketogenic diet can be an effective anticonvulsant treatment in some pediatric patients with pharmacoresistant epilepsy. Its mechanism(s) of action, however, remain uncertain. Direct sampling of cerebrospinal fluid before and during metabolic therapy may rev...

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Detalles Bibliográficos
Autores principales: Masino, Susan A., Ruskin, David N., Freedgood, Natalie R., Lindefeldt, Marie, Dahlin, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923458/
https://www.ncbi.nlm.nih.gov/pubmed/33648550
http://dx.doi.org/10.1186/s12986-020-00524-1