Sequential and co-occurring DNA damage response genetic mutations impact survival in stage III colorectal cancer patients receiving adjuvant oxaliplatin-based chemotherapy

BACKGROUND: Certain sequences of genomic mutations can lead to cancer formation and affect treatment outcomes and drug resistance. We constructed a cancer evolutionary tree using bulk-targeted deep sequencing to explore the impact of sequential and co-occurring somatic mutations on patients with sta...

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Detalles Bibliográficos
Autores principales: Lin, Peng-Chan, Yeh, Yu-Min, Chan, Ren-Hao, Lin, Bo-Wen, Chen, Po-Chuan, Pan, Chien-Chang, Shen, Meng-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923464/
https://www.ncbi.nlm.nih.gov/pubmed/33653301
http://dx.doi.org/10.1186/s12885-021-07926-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923464/
https://www.ncbi.nlm.nih.gov/pubmed/33653301
http://dx.doi.org/10.1186/s12885-021-07926-1

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