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GM-CSF enhanced the effect of CHOP and R-CHOP on inhibiting diffuse large B-cell lymphoma progression via influencing the macrophage polarization

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is a common type of the Non-Hodgkin lymphomas (NHLs) formed by the neoplastic transformation of mature B cells. As the first-line therapeutics, CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and R-CHOP (Rituximab + CHOP), eit...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Xiang, Jingjing, Sheng, Xianfu, Zhu, Ni, Deng, Shu, Chen, Junfa, Yu, Lihong, Zhou, Yan, Lin, Chenjun, Shen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923488/
https://www.ncbi.nlm.nih.gov/pubmed/33653348
http://dx.doi.org/10.1186/s12935-021-01838-7