PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants

BACKGROUND: The rapid expansion of the CRISPR toolbox through tagging effector domains to either enzymatically inactive Cas9 (dCas9) or Cas9 nickase (nCas9) has led to several promising new gene editing strategies. Recent additions include CRISPR cytosine or adenine base editors (CBEs and ABEs) and...

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Detalles Bibliográficos
Autores principales: Siegner, Sebastian M., Karasu, Mehmet E., Schröder, Markus S., Kontarakis, Zacharias, Corn, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923538/
https://www.ncbi.nlm.nih.gov/pubmed/33653259
http://dx.doi.org/10.1186/s12859-021-04034-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923538/
https://www.ncbi.nlm.nih.gov/pubmed/33653259
http://dx.doi.org/10.1186/s12859-021-04034-6

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