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Transiently structured head domains control intermediate filament assembly
Low complexity (LC) head domains 92 and 108 residues in length are, respectively, required for assembly of neurofilament light (NFL) and desmin intermediate filaments (IFs). As studied in isolation, these IF head domains interconvert between states of conformational disorder and labile, β-strand–enr...
Autores principales: | Zhou, Xiaoming, Lin, Yi, Kato, Masato, Mori, Eiichiro, Liszczak, Glen, Sutherland, Lillian, Sysoev, Vasiliy O., Murray, Dylan T., Tycko, Robert, McKnight, Steven L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923618/ https://www.ncbi.nlm.nih.gov/pubmed/33593918 http://dx.doi.org/10.1073/pnas.2022121118 |
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