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Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1

Paired box protein 5 (Pax5) is a crucial transcription factor responsible for B-cell lineage specification and commitment. In this study, we identified a negative role of Pax5 in osteoclastogenesis. The expression of Pax5 was time-dependently downregulated by receptor activator of nuclear factor kap...

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Detalles Bibliográficos
Autores principales: Yu, Jiyeon, Kim, Sumi, Lee, Nari, Jeon, Hyoeun, Lee, Jun, Takami, Masamichi, Rho, Jaerang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923754/
https://www.ncbi.nlm.nih.gov/pubmed/33672551
http://dx.doi.org/10.3390/ijms22042097