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AMPAkines potentiate the corticostriatal pathway to reduce acute and chronic pain

The corticostriatal circuit plays an important role in the regulation of reward- and aversion-types of behaviors. Specifically, the projection from the prelimbic cortex (PL) to the nucleus accumbens (NAc) has been shown to regulate sensory and affective aspects of pain in a number of rodent models....

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Detalles Bibliográficos
Autores principales: Zeng, Fei, Zhang, Qiaosheng, Liu, Yaling, Sun, Guanghao, Li, Anna, Talay, Robert S., Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923831/
https://www.ncbi.nlm.nih.gov/pubmed/33653395
http://dx.doi.org/10.1186/s13041-021-00757-y