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A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator

Palmitoylethanolamide (PEA) is an endogenous anti-inflammatory lipid mediator and a widely used nutraceutical. In this study, we designed, realized, and tested a drug-carrier conjugate between PEA (the active drug) and glucuronic acid (the carrier). The conjugate, named GLUPEA, was characterized for...

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Detalles Bibliográficos
Autores principales: Manzo, Emiliano, Schiano Moriello, Aniello, Tinto, Francesco, Verde, Roberta, Allarà, Marco, De Petrocellis, Luciano, Pagano, Ester, Izzo, Angelo A., Di Marzo, Vincenzo, Petrosino, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924038/
https://www.ncbi.nlm.nih.gov/pubmed/33672574
http://dx.doi.org/10.3390/cells10020450