The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

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Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics. This identified viral proteins at specific intrace...

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Detalles Bibliográficos
Autores principales: Meyers, Jordan M, Ramanathan, Muthukumar, Shanderson, Ronald L, Donohue, Laura, Ferguson, Ian, Guo, Margaret G, Rao, Deepti S, Miao, Weili, Reynolds, David, Yang, Xue, Zhao, Yang, Yang, Yen-Yu, Wang, Yinsheng, Khavari, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924263/
https://www.ncbi.nlm.nih.gov/pubmed/33655243
http://dx.doi.org/10.1101/2021.02.23.432450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924263/
https://www.ncbi.nlm.nih.gov/pubmed/33655243
http://dx.doi.org/10.1101/2021.02.23.432450

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