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The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics. This identified viral proteins at specific intrace...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924263/ https://www.ncbi.nlm.nih.gov/pubmed/33655243 http://dx.doi.org/10.1101/2021.02.23.432450 |
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por Meyers, Jordan M., Ramanathan, Muthukumar, Shanderson, Ronald L., Beck, Aimee, Donohue, Laura, Ferguson, Ian, Guo, Margaret G., Rao, Deepti S., Miao, Weili, Reynolds, David, Yang, Xue, Zhao, Yang, Yang, Yen-Yu, Blish, Catherine, Wang, Yinsheng, Khavari, Paul A.
Publicado 2021
Enlace del recurso
Publicado 2021
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Online
Artículo
Texto