Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors

Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABA(A) receptors (GABA(A)Rs) with different efficacy, an important role of the TFTs central loop in binding to these receptors...

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Detalles Bibliográficos
Autores principales: Son, Lina, Kryukova, Elena, Ziganshin, Rustam, Andreeva, Tatyana, Kudryavtsev, Denis, Kasheverov, Igor, Tsetlin, Victor, Utkin, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924340/
https://www.ncbi.nlm.nih.gov/pubmed/33672715
http://dx.doi.org/10.3390/toxins13020164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924340/
https://www.ncbi.nlm.nih.gov/pubmed/33672715
http://dx.doi.org/10.3390/toxins13020164

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