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Wnt/β-Catenin Signaling and Immunotherapy Resistance: Lessons for the Treatment of Urothelial Carcinoma

SIMPLE SUMMARY: Metastatic urothelial cell carcinoma (UCC) is a significant public health burden with a median survival estimated at about 15 months. The use of immunotherapy with immune checkpoint inhibitors has greatly improved outcomes but only benefits a minority (~20%) of patients. In this revi...

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Detalles Bibliográficos
Autores principales: Chehrazi-Raffle, Alexander, Dorff, Tanya B., Pal, Sumanta K., Lyou, Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924395/
https://www.ncbi.nlm.nih.gov/pubmed/33672668
http://dx.doi.org/10.3390/cancers13040889