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RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

Mutations in RanBP2 (also known as Nup358), one of the main components of the cytoplasmic filaments of the nuclear pore complex, contribute to the overproduction of acute necrotizing encephalopathy (ANE1)-associated cytokines. Here we report that RanBP2 represses the translation of the interleukin 6...

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Detalles Bibliográficos
Autores principales: Shen, Qingtang, Wang, Yifan E., Truong, Mathew, Mahadevan, Kohila, Wu, Jingze J., Zhang, Hui, Li, Jiawei, Smith, Harrison W., Smibert, Craig A., Palazzo, Alexander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924746/
https://www.ncbi.nlm.nih.gov/pubmed/33600493
http://dx.doi.org/10.1371/journal.pgen.1009378